The Whispers of Biology

  Not long ago, someone asked me: “Working in a company might be repetitive — not as daring or unpredictable as academic research. Would you still be interested?” Then I came across the story of the Nobel laureates who discovered G-protein-coupled receptors (GPCRs) — Drs. Brian Kobilka and Robert Lefkowitz — and my perspective completely shifted.

  I had to analyze data from 96- or 384-well plates — each exported as a CSV file with thousands of rows. Sounds familiar? Yes! 96 or 384 wells — the well plates from the wet lab. My data came from 2D cell culture imaging, where I had to analyze single-cell information. I opened each file, searched for specific values, and repeated the same thing again and again. What I faced were: - Finger pain 😂 - Human weakness → human error after half a day of doing this - Forgetting to save → all work gone - Changing cut-offs → meant redoing everything from the start (and you know how often supervisors change them!) I realized all of this was just repetition. I knew every step — I just had to do it again for every well (or many plates). So I told my supervisor I wanted to use coding/programming to automate it. His answer? No. He wanted me to do it manually — “by eyes” — to get results faster. But I believed I could do more. So I decided to learn coding (R) secretly. I didn’t tell him — I ...

  Let’s break it down scene by scene so it’s easy to follow. Ready? Let’s roll! 🎬 🎬 Scene 1: The War Inside the Body Inside our body lives a massive army of dinosaur soldiers —our immune system— guarding the city of “Bodyville” from enemies like viruses, bacteria, and cancer cells. They’re always ready for battle— but here’s the catch… sometimes, these dino-soldiers go berserk! 😱 They start firing at everything in sight— even innocent citizens like the liver, eyes, or skin. And that’s how autoimmune diseases begin— when your body’s own army can’t tell friend from foe. 🦕 Scene 2: Enter the Boss – T-Rex the Peacemaker In 2025 , the Nobel Prize in Physiology or Medicine 🏅 was awarded to Mary Brunkow , Fred Ramsdell , and Shimon Sakaguchi for discovering the Regulatory T cell (Treg) — the real-life T-Rex boss of the immune army! 🦖 Yes, this T-Rex doesn’t roar to fight — it roars to calm the troops down . 🧠 Scene 3: The Birth of the T-Reg Unit Tregs are t...